A wealthy man named Clayton Beresford Jr. (Hayden Christensen) has a faulty heart and needs a heart transplant. Against his mother's wishes, he will be operated on by his surgeon friend, Jack (Terrence Howard), instead of a prestigious doctor. He is also dating his mother's secretary Sam (played by Alba), whom he marries on the eve of the surgery. However, when he finds that he is still awake during the operation (a phenomenon called anesthesia awareness), he finds out about a plot to kill him and get his money, and learns that Jack and Sam are in on it. Eventually, his mother catches on and sacrifices herself to let Clayton have her compatible heart. The film ends with hospital security arresting all the corrupt doctors except Jack, who has locked himself inside his office. His respite is short-lived however, as a locksmith is seen in the last scene, undoing the lock in the door. He also has evidence in his hands showing that Sam was in the room during surgery. Meanwhile, Sam attempts to escape by using one of the hospital's Emergency Exit doors but is apprehended by authorities. Wikipedia